Low molecular weight heparin versus unfractionated heparin following thrombolysis in myocardial infarction
نویسندگان
چکیده
منابع مشابه
Unfractionated and low molecular weight heparin
Background Unfractionated heparin (UFH) is mostly obtained from porcine and bovine mucosa and has been widely used for the treatment and prevention of thrombotic events. It consists of molecular chains of various lengths varying from 2000 to 40,000 Da [1]. Low molecular weight heparins (LMWHs) are smaller chains of UFH that can be obtained, from unfractionated heparin, by various chemical and e...
متن کاملLow molecular weight heparin versus unfractionated heparin in the initial treatment of venous thromboembolism.
In this review, we analyze data from randomized trials in which low molecular weight heparin was compared with unfractionated heparin, both to estimate the treatment effect of low molecular weight heparin in the initial treatment of venous thromboembolism and to evaluate the effect of the varied proportion of included cancer patients (6% to 22.7%) on the incidence of outcome events (recurrence ...
متن کاملLow-molecular-weight heparin as an adjunct to thrombolysis in ST elevation myocardial infarction.
T he Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment (ExTRACT)–Thrombolysis in Myocardial Infarction (TIMI)-25 study demonstrated that the administration of enoxaparin sodium, 30 mg intravenously, followed by subcutaneous injections of 1 mg/kg twice daily (dose modified in patients 75 years or older), compared with intravenous unfractionated heparin (UFH), 60 U...
متن کاملAngiographic and clinical outcomes in patients receiving low-molecular-weight heparin versus unfractionated heparin in ST-elevation myocardial infarction treated with fibrinolytics in the CLARITY-TIMI 28 Trial.
BACKGROUND Low-molecular-weight heparin (LMWH) offers pharmacological and practical advantages over unfractionated heparin (UFH). Whether these advantages translate into greater infarct-related artery patency and fewer adverse clinical events in patients with ST-elevation myocardial infarction (STEMI) receiving fibrinolytic therapy remains under study. METHODS AND RESULTS We compared angiogra...
متن کاملLow-molecular-weight heparin versus unfractionated heparin in acute ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention with drug-eluting stents.
BACKGROUND Whether low-molecular-weight heparin (LMWH) is superior to unfractionated heparin (UFH) in acute ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) with drug-eluting stents (DESs) remains unclear. METHODS A total of 3,372 STEMI patients who underwent primary PCI with DESs received either LMWH (n = 1,531 patients, ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1998
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(98)81472-1